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Global Foundation for Peroxisomal Disorders



Address

5147 South Harvard Avenue
Suite 181
Tulsa, OK 74135

Phone

3474704373

Fax

9185160227

Email Address

[email protected]

Description

The Global Foundation for Peroxisomal Disorders (GFPD) is a voluntary organization whose mission is to help children and families faced with a diagnosis of peroxisomal biogenesis disorders, also known as Zellweger spectrum of disorders. GFPD strives to assist family members and professionals through educational programs, research, and support services. Peroxisome biogenesis disorders (PBDs) are a group of disorders characterized by the failure of the body to produce peroxisomes that function properly. Peroxisomes are very small, membrane-bound structures within the gel-like fluid (cytoplasm) of cells that play a vital role in numerous biochemical processes in the body. PBDs are subdivided into the three Zellweger spectrum disorders. Zellweger spectrum disorders are a group of rare, genetic, multisystem disorders that were once thought to be separate entities. These disorders are now classified as different expressions (variants) of one disease process. Collectively, they form a spectrum or continuum of disease. Zellweger syndrome is the most severe form; neonatal adrenoleukodystrophy is the intermediate form; and infantile Refsum disease is the mildest form.

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